Leggio awakens to discover alien creatures mutating the corpses in the morgue, which then kill him.

Vincent and her security teammates Ramirez (Hal Sparks), Hanson (Phil Morris), Dobbs (Bennett), Pendleton (Kevin Michael Richardson), and Shen (Kelly Hu) are dispatched to arrest and quarantine the people on the shuttle, but they find nothing aboard but pools of blood. Barrow's shuttle crashes into the Ishimura's hangar, just as he is killed by his mutated wife. He orders that the planet be quarantined and return to Earth with the Marker. The captain refuses to radio for help, as he would face a court martial for entering a restricted system. The Ishimura re-establishes links with the colony, receiving evidence of a massacre. Barrow takes her body and flees the facility in a shuttle, unaware of an alien presence attached to the corpse. One man, Farum (Cummings) vanishes during a blackout, while the other, Colin Barrow (Bruce Boxleitner) sees his wife Jen (Lia Sargent) commit suicide. Meanwhile, two miners on Aegis VII check an outpost that has gone silent. While the Ishimura extracts a chunk of the planet to mine, a man in the ship's sick bay, Hans Leggio, (Jeff Bennett) struggles against his restraints and resists sedation, begging to be killed. Head of Security Alissa Vincent (Nika Futterman) asks to investigate the colony, but Mathius believes nothing is amiss.

The Marker is brought aboard by order of Captain Benjamin Mathius (Jim Cummings). While the ship approaches, they receive radio reports of an outbreak of violent behavior among the colonists. The Church of Unitology uses its influence to send the mining ship USG Ishimura to retrieve this holy relic. An alien artifact, identified as a possible 'second Marker', is discovered on the planet Aegis VII.

Animated dead space cartoon